Is ZEJULA Right for You?
Whether you are considering a maintenance treatment or simply wondering what the next step will be after chemotherapy, your doctor can help you find the right choice for you.
ZEJULA may be right for you if you are a woman diagnosed with recurrent ovarian, fallopian tube, or primary peritoneal cancer that has1
- Previously been treated with 2 or more courses of platinum-based chemotherapy, and
- Responded (completely or partially) to the most recent treatment
ZEJULA offers more time without your cancer recurring, regardless of BRCA status1
One of the ways ZEJULA was studied was by looking at information gathered during the clinical trial about how long women lived without progression. One analysis estimated the likelihood of progression during specific time points, such as 2 years after beginning therapy. This estimated how likely it was that women participating in the study were still receiving ZEJULA or placebo at 2 years.2,3*
After 2 years of treatment with ZEJULA, it was estimated that†
of women who were BRCA-positive‡ would not experience progression of their recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer compared with 16% who did not receive ZEJULA3
of women who were BRCA-negative§ would not experience progression of their recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer compared with 12% who did not receive ZEJULA3
Estimated long-term PFS of 24 months.
*Patients in the study whose cancer progression status was unknown were not included in this analysis.2
†Long-term information about overall survival is not yet available.2
‡Had an inherited mutation.
§Did not have an inherited mutation.
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References: 1. ZEJULA [package insert]. Waltham, MA: TESARO, Inc; 2018. 2. Mirza MR, Monk BJ, Herrstedt J, et al; for the ENGOT-OV16/NOVA investigators. Niraparib maintenance therapy in platinum-sensitive, recurrent ovarian cancer. N Engl J Med. 2016:375(22):2154-2164. 3. Data on file. TESARO, Inc.