Glossary of Terms

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D

Deductible – The specified amount that you must pay for services or procedures before your insurance company contributes.17

Denial – A decision made by your insurance company that a service or treatment is not covered. This is usually communicated in a letter to you or your healthcare team. This decision may be based on eligibility criteria.1,18

Dose Adjustment – Your healthcare team may adjust your dose of ZEJULA based on how you feel or the results of your lab work. This may also be called a dose modification or dose reduction.14,19

Double-blind, placebo-controlled – In a double-blind, placebo-controlled trial, some participants are given the treatment, while others are given a placebo (sugar pill). Neither the researchers nor the participants know which treatment the participants receive until the trial has ended, which is why they are referred to as “blind.” This is the gold standard for clinical trials because it minimizes the chance of a therapeutic effect being detected when no effect is present.

Support
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Asked Questions

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National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/somatic-mutation. Accessed May 4, 2018. 14. ZEJULA [package insert]. Waltham, MA: TESARO, Inc; 2018. 15. NCI Dictionary of Cancer Terms: Complete Blood Count. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/complete-blood-count. Accessed May 4, 2018. 16. U.S. Centers for Medicare & Medicaid Services Glossary: Copayment. HealthCare.gov. https://www.healthcare.gov/glossary/co-payment/. Accessed May 4, 2018. 17. U.S. Centers for Medicare & Medicaid Services Glossary: Deductible. HealthCare.gov. https://www.healthcare.gov/glossary/deductible/. Accessed May 4, 2018. 18. U.S. Centers for Medicare & Medicaid Services. Internal appeals. HealthCare.gov. https://www.healthcare.gov/appeal-insurance/internal-appeals/. Accessed May 4, 2018. 19. Data on file, PR-30-5011-C. TESARO, Inc. 20. NCI Dictionary of Cancer Terms: Explanation of Benefits. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/explanation-of-benefits. Accessed May 4, 2018. 21. NCI Dictionary of Cancer Terms: Food and Drug Administration. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/fda. Accessed May 4, 2018. 22. Office for Civil Rights. What does the HIPAA Privacy Rule do? HHS.gov. https://www.hhs.gov/hipaa/for-individuals/faq/187/what-does-the-hipaa-privacy-rule-do/index.html. Accessed May 4, 2018. 23. Fair Health Glossary: Health Insurance Portability and Accountability Act. Fair Health Consumer. http://www.fairhealthconsumer.org/glossary. Accessed May 4, 2018. 24. Chen Y, Zhang L, Liu WX, Liu XY. Prognostic significance of preoperative anemia, leukocytosis and thrombocytosis in chinese women with epithelial ovarian cancer. Asian Pac J Cancer Prev. 2015;16(3):933-939. 25. Health Insurance Glossary. California’s Valued Trust. https://www.cvtrust.org/sites/default/files/media/downloads/HealthInsuranceGlossary.pdf. Accessed May 4, 2018. 26. NCI Dictionary of Cancer Terms: Maintenance Treatment. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/maintenance-therapy. Accessed May 4, 2018. 27. Merriam-Webster Dictionary: Median. Merriam-Webster website. https://www.merriam-webster.com/dictionary/median. Accessed May 4, 2018. 28. Hofmann SG, Sawyer AT, Witt AA, Oh D. The effect of mindfulness-based therapy on anxiety and depression: a meta-analytic review. J Consult Clin Psychol. 2010;78(2):169-183. 29. NCI Dictionary of Cancer Terms: Neutropenia. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/neutropenia. Accessed May 4, 2018. 30. American Cancer Society. Low white blood cell (neutrophil) counts and the risk of infection. American Cancer Society website. https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/infections/infections-in-people-with-cancer/low-wbc-and-weak-immune-system.html. Accessed May 4, 2018. 31. NCI Dictionary of Cancer Terms: Off-label. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/off-label. Accessed May 4, 2018. 32. Thornton RG. Package inserts and the standard of care. Proc (Bayl Univ Med Cent). 2003;16(4):502-504. 33. NCI Dictionary of Cancer Terms: PARP Inhibitor. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/parp-inhibitor. Accessed May 4, 2018. 34. Sandhu SK, Schelman WR, Wilding G, et al. The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial. Lancet Oncol. 2013;14(9):882-892. 35. NCI Dictionary of Cancer Terms: Pharmacist. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/pharmacist. Accessed May 4, 2018. 36. NCI Dictionary of Cancer Terms: Platelet. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/platelet. Accessed May 4, 2018. 37. Chemotherapy. Ovarian Cancer Research Fund Alliance. https://ocrfa.org/patients/about-ovarian-cancer/treatment/chemotherapy/. Accessed May 4, 2018. 38. NCI Dictionary of Cancer Terms: Platinum. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/platinum. Accessed May 4, 2018. 39. U.S. Centers for Medicare & Medicaid Services Glossary: Premium. HealthCare.gov. https://www.healthcare.gov/glossary/premium/. Accessed May 4, 2018. 40. NCI Dictionary of Cancer Terms: Progression-free Survival. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/progression-free-survival. Accessed May 4, 2018. 41. NCI Dictionary of Cancer Terms: Red Blood Cell. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/red-blood-cell. Accessed May 4, 2018. 42. NCI Dictionary of Cancer Terms: Remission. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/remission. Accessed May 4, 2018. 43. NCI Dictionary of Cancer Terms: Response. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/response. Accessed May 4, 2018. 44. Merriam-Webster Dictionary: Threshold. Merriam-Webster website. https://www.merriam-webster.com/dictionary/threshold. Accessed May 4, 2018. 45. NCI Dictionary of Cancer Terms: Thrombocytopenia. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/thrombocytopenia. Accessed May 4, 2018. 46. U.S. Centers for Medicare & Medicaid Services Glossary: UCR (Usual, Customary, and Reasonable). HealthCare.gov. https://www.healthcare.gov/glossary/ucr-usual-customary-and-reasonable/. Accessed May 4, 2018. 47. NCI Dictionary of Cancer Terms: Watchful Waiting. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/watchful-waiting. Accessed May 4, 2018. 48. NCI Dictionary of Cancer Terms: White Blood Cell. National Cancer Institute website. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/white-blood-cell. Accessed May 4, 2018.

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